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Linda A McKown Selected Research

1,2,3,5- tetrahydro- 6- methoxy- N- (4- methoxyphenyl)- 5- methyl- 3- oxopyrido(1,2- a)benzimidazole- 4- carboxamide

10/2006Metabolism of the new anxiolytic agent, a pyrido[1,2-]benzimidazole (PBI) analog (RWJ-53050), in rat and human hepatic S9 fractions, and in dog; identification of cytochrome p450 isoforms mediated in the human microsomal metabolism.

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Linda A McKown Research Topics

Disease

2Dehydration (Water Stress)
10/2006 - 08/2003
1Body Weight (Weight, Body)
04/2002
1Fever (Fevers)
04/2002
1Infections
04/2002

Drug/Important Bio-Agent (IBA)

11,2,3,5- tetrahydro- 6- methoxy- N- (4- methoxyphenyl)- 5- methyl- 3- oxopyrido(1,2- a)benzimidazole- 4- carboxamideIBA
10/2006
17- fluoro- 1,2- dihydro- 3- oxo- N- (2,6- diflurophenyl)pyrido(1,2- alpha)benzimidazole- 4- carboxamideIBA
08/2003
1Cyclopentanes (Cyclopentane)IBA
04/2002
1peramivirIBA
04/2002
1Neuraminidase (Sialidase)IBA
04/2002
1Antiviral Agents (Antivirals)IBA
04/2002

Therapy/Procedure

1Oral Administration
04/2002